You already own the most personal data there is. Premno connects it to the people advancing human genetics.
Compatibility is not an endorsement. After downloading your files, review the provider's retention and deletion controls. Premno reads the copy stored on your device.
Millions of people have sequenced their DNA. But the analysis you got was a one-time product — frozen the day you bought it, while the science kept moving.
Providers analyse your data once, at the point of sale. After that they have little reason to keep your report current.
Insights live inside their portal, in their format, on their terms — even though the genome is unmistakably yours.
New genes, risk models and drug-response findings ship every week in labs and repos — and almost none of it reaches you.
Drop in a 23andMe export or whole-genome files — FASTQ, BAM or VCF. They stay on your own disk, always.
Choose an analysis from your installed packages or the marketplace. Each one is a self-contained, documented pipeline.
Premno runs it in an isolated container and hands back a plain-language report you can actually read — plus the raw outputs.
If the budget allows, choose 30× paired-end whole-genome sequencing. It gives you the strongest reusable foundation. The lower-cost options still have a place—here is exactly what each one buys you.
A DNA array checks a fixed list of known positions. It is inexpensive and the files are small, but anything outside that list remains invisible.
Useful if you already have one. We would not buy it solely for Premno.
Paired-end reads sample the whole genome at low depth. It offers broader common-variant coverage than a marker array, especially after imputation.
Good breadth for the price, but not dependable for individual rare variants.
Paired-end reads cover each position many times, producing the most reusable general-purpose genome for current and future analyses.
Choose 2 × 150 bp reads and insist on downloading the complete raw files.
Confirm these details in writing. They determine whether you can keep learning from the same sample as the science changes.
We do not currently list a marker-array provider: none we reviewed met this deletion standard. Premno has no affiliation with the providers above; future partnerships will always be clearly labelled. Prices are indicative before shipping and taxes and may change. For research and informational use only. If you are investigating a medical concern, choose testing with a qualified clinician or genetic counsellor.
No command line, no jargon. Ask about your genome the way you'd text a friend who happens to be a geneticist — Premno runs the right analysis on your own machine and explains what it finds, in words that actually mean something.
A readable overview of well-studied variants and what current research says about them.
health-core:2.2See how your genes may influence your response to common medications and dosages.
pgx-core:1.4Population-calibrated risk estimates for complex conditions, from large GWAS panels.
prs-cvd:2.0Recessive variants worth knowing about — especially when planning a family — from WGS data.
carrier-screen:3.1Fine-grained ancestry composition and deep lineage from your whole genome, not a chip.
ancestry:2.0ACMG-style interpretation of specific variants, with the evidence trail behind each call.
clinvar-interpret:1.2Every analysis is a Package — a containerised pipeline with clear docs. Premno ships with free core packages, and researchers publish more, free or paid.
Every package is checked by our team before it reaches you.
Use the free core set, or unlock specialist pipelines from researchers.
Pinned containers mean a run today reproduces exactly tomorrow.
This is the most personal data you'll ever have. Premno is a desktop app precisely so your genome can stay exactly where it belongs — with you.
Pipelines run in isolated containers on your own machine — not our servers.
We never upload or keep your genetic data. There is nothing of yours on our side to leak.
Import, export or delete anything at any time. Your data, your rules, always.
Every package is a transparent, versioned container you're free to audit.
Your work shouldn't be stuck in a repo and a paper. Package your container in the Researcher Portal, add the docs, and reach real people with real genomes — for free or for a fee.
A raw-data export from a service like 23andMe or AncestryDNA works, and so do whole-genome files (FASTQ, BAM or VCF) from any sequencing provider. Each package lists exactly what it accepts.
Yes. Premno runs on your computer and analyses your files locally, inside isolated containers. We never upload or store your genetic data — it never leaves your device.
Not at all. The Assistant guides you in plain language — pick what you want and it runs the pipeline for you. If you are technical, the Expert workspace gives you full control over files, runs and logs.
The app and a set of core packages are free. Some specialist packages from researchers are paid, priced by their authors — you'll always see the price before you install.
Premno is a desktop app for macOS and Windows. A cloud version may come later, but the local-first app is the heart of the product.
No. Premno is for research and informational purposes and is not a diagnostic tool. Always talk to a qualified clinician or genetic counsellor before acting on anything you learn here.
We're opening access in waves. Leave your email and we'll invite you as soon as Premno is ready on your platform.